SOD Cu-Zn/SOD1: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD

It's the GeneMedi's summary page for Target/Biomarker Introduction of SOD Cu-Zn/SOD1. The page also collects GeneMedi's different modalities and formats products for SOD Cu-Zn in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the SOD Cu-Zn target is also connected to human indications/diseases/conditions/MOA.

Target sublocation: Transmembrane Protein.

The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. In addition, this protein contains an antimicrobial peptide that displays antibacterial, antifungal, and anti-MRSA activity against E. coli, E. faecalis, S. aureus, S. aureus MRSA LPV+, S. agalactiae, and yeast C. krusei. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq, Jul 2020]

Target IDGM-T22977
Target NameSOD Cu-Zn
Gene ID6647,20655,24786,574096,403559,101091804,281495,100033855
Gene Symbol and SynonymsALS,ALS1,B430204E11Rik,Cu/Zn-SOD,CuZnSOD,HEL-S-44,homodimer,hSod1,Ipo-1,Ipo1,IPOA,SOD,Sod-1,SOD1,SOD1L1,SODC,STAHP
Uniprot AccessionP00441,P07632,Q8HXQ0,Q8WNN6,P00442,P00443
Uniprot Entry NameSODC_HUMAN,SODC_MACMU,SODC_RAT,SODC_CANLF,SODC_BOVIN,SODC_HORSE
Protein Sub-locationTransmembrane Protein
CategoryTherapeutics Target
DiseaseLung Cancer, ALS
Gene EnsemblENSG00000142168
Target ClassificationN/A


Pre-made anti-SOD Cu-Zn inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research

Pre-made anti-SOD Cu-Zn benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-SOD Cu-Zn mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Antibody NameSpeciesFormatClassified by tagDetail
Anti-SOD Cu-Zn/SOD1 monoclonal antibodyHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquinemabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail



Multi-species SODC/ SOD Cu-Zn/ SOD1 VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SOD Cu-Zn/SOD1 VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Products NameSpeciesExpression PlatformDetail
SOD Cu-Zn/SOD1 VLP (virus-like particle)Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquineMammalian cellProducts Developing



Pre-made SOD1 viral vector in GM Promise-ORFTM

Cat No.Products nameNM IDSpeciesTypeDetail
vGMLP000506human SOD1 Lentivirus particleNM_000454HumanLentivirus particleDetail
pGMLP000506human SOD1 Lentivirus plasmidNM_000454HumanLentivirus plasmidDetail
vGMAP000004Human SOD1 Adenovirus particleBC001034HumanAdenovirus particleDetail
pGMAP000004Human SOD1 Adenovirus plasmidBC001034HumanAdenovirus plasmidDetail
pGMLPm000209mouse Sod1 Lentivirus plasmidNM_011434MouseLentivirus plasmidDetail
vGMLPm000209mouse Sod1 Lentivirus particleNM_011434MouseLentivirus particleDetail

About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI

If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.