HBEGF: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of HBEGF. The page also collects GeneMedi's different modalities and formats products for HBEGF in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the HBEGF target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Transmembrane Protein.
Enables growth factor activity and heparin binding activity. Involved in several processes, including epidermal growth factor receptor signaling pathway; positive regulation of protein kinase B signaling; and positive regulation of wound healing. Located in cell surface and extracellular space. Implicated in glomerulosclerosis and perinatal necrotizing enterocolitis. [provided by Alliance of Genome Resources, Apr 2022]
| Target ID | GM-T76093 |
| Target Name | HBEGF |
| Gene ID | 1839,15200,25433,695559,607007,101093578,522921,100629956 |
| Gene Symbol and Synonyms | DTR,DTS,DTSF,GFHB,Hb-egf,HBEGF,HEGFL |
| Uniprot Accession | Q99075,Q06175 |
| Uniprot Entry Name | HBEGF_HUMAN,HBEGF_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target |
| Disease | Urinary Tract Infection, Overactive bladder |
| Gene Ensembl | ENSG00000113070 |
| Target Classification | N/A |
Pre-made anti-HBEGF inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-HBEGF benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-HBEGF mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
| Antibody Name | Species | Format | Classified by tag | Detail |
| Anti-HBEGF monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Multi-species HBEGF/ DTR/ DTS VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HBEGF VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
| Products Name | Species | Expression Platform | Detail |
| HBEGF VLP (virus-like particle) | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Products Developing |
Pre-made HBEGF viral vector in GM Promise-ORFTM
| Cat No. | Products name | NM ID | Species | Type | Detail |
| vGMLP000457 | human HBEGF Lentivirus particle | NM_001945 | Human | Lentivirus particle | Detail |
| pGMLP000457 | human HBEGF Lentivirus plasmid | NM_001945 | Human | Lentivirus plasmid | Detail |
| pGMAP000278 | Human HBEGF Adenovirus plasmid | BC033097 | Human | Adenovirus plasmid | Detail |
| vGMAP000278 | Human HBEGF Adenovirus particle | BC033097 | Human | Adenovirus particle | Detail |
| pGMLPm001015 | mouse Hbegf Lentivirus plasmid | NM_010415 | Mouse | Lentivirus plasmid | Detail |
| vGMLPm001015 | mouse Hbegf Lentivirus particle | NM_010415 | Mouse | Lentivirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.