Human TTR/ATTR/CTS ORF/cDNA clone-Lentivirus plasmid (NM_000371)

Cat. No.: pGMLP000332
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human TTR/ATTR/CTS Lentiviral expression plasmid for TTR lentivirus packaging, TTR lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Go to Prealbumin/transthyretin/TTR/TTR/ATTR products collection>>
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Product Description

Catalog ID pGMLP000332
Gene Name TTR
Accession Number NM_000371
Gene ID 7276
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 444 bp
Gene Alias ATTR,CTS,CTS1,HEL111,HsT2651,PALB,TBPA
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGGCTTCTCATCGTCTGCTCCTCCTCTGCCTTGCTGGACTGGTATTTGTGTCTGAGGCTGGCCCTACGGGCACCGGTGAATCCAAGTGTCCTCTGATGGTCAAAGTTCTAGATGCTGTCCGAGGCAGTCCTGCCATCAATGTGGCCGTGCATGTGTTCAGAAAGGCTGCTGATGACACCTGGGAGCCATTTGCCTCTGGGAAAACCAGTGAGTCTGGAGAGCTGCATGGGCTCACAACTGAGGAGGAATTTGTAGAAGGGATATACAAAGTGGAAATAGACACCAAATCTTACTGGAAGGCACTTGGCATCTCCCCATTCCATGAGCATGCAGAGGTGGTATTCACAGCCAACGACTCCGGCCCCCGCCGCTACACCATTGCCGCCCTGCTGAGCCCCTACTCCTATTCCACCACGGCTGTCGTCACCAATCCCAAGGAATGA
ORF Protein Sequence MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T86462-Ab Anti-TTHY/ TTR/ ATTR functional antibody
    Target Antigen GM-Tg-g-T86462-Ag TTR protein
    ORF Viral Vector pGMLP000332 Human TTR Lentivirus plasmid
    ORF Viral Vector pGMLP002013 Human TTR Lentivirus plasmid
    ORF Viral Vector pGMAP000187 Human TTR Adenovirus plasmid
    ORF Viral Vector pGMPC001668 Human TTR Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP000332 Human TTR Lentivirus particle
    ORF Viral Vector vGMLP002013 Human TTR Lentivirus particle
    ORF Viral Vector vGMAP000187 Human TTR Adenovirus particle


    Target information

    Target ID GM-T86462
    Target Name Prealbumin/transthyretin/TTR
    Gene Group Identifier
    （Target Gene ID in Homo species)         		7276
    Gene ID 100052147 (Equus caballus), 101085927 (Felis catus), 22139 (Mus musculus), 24856 (Rattus norvegicus)
    280948 (Bos taurus), 480167 (Canis lupus familiaris), 705943 (Macaca mulatta), 7276 (Homo sapiens)
    Gene Symbols & Synonyms TTR,Ttr,prealbumin,TT,Lr1,Tbpa,TTR1,CTS,TTN,ATTR,CTS1,PALB,TBPA,HEL111,HsT2651
    Target Alternative Names ATTR,CTS,CTS1,HEL111,HsT2651,Lr1,PALB,Prealbumin,TBPA,TT,TTN,TTR,TTR1,Tbpa,Transthyretin,Ttr,prealbumin,transthyretin
    Uniprot Accession O46375,P02766,P02767,P07309
    Additional SwissProt Accessions: P07309,P02767,O46375,P02766
    Uniprot Entry Name
    Protein Sub-location Secreted Protein/Potential Cytokines
    Category Therapeutics Target
    Disease Ovary Cancer, hepatitis B, ovarian cancer, Diabetic Nephropathy, Alzheimer's Disease, Choroid plexus tumors, Dent disease, IgA glomerulonephritis, Nephrotic syndrome with focal and segmental glomerular lesions, Type 2 diabetes mellitus
    Disease from KEGG Thyroid hormone synthesis
    Gene Ensembl ENSECAG00000015875, ENSMUSG00000061808, ENSBTAG00000010991, ENSCAFG00845010593, ENSMMUG00000052277, ENSG00000118271
    Target Classification


    About GMVC

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    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.