Human CFLAR/c-FLIP/c-FLIPL ORF/cDNA clone-Lentivirus plasmid (NM_001127183)

Cat. No.: pGMLP000484
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human CFLAR/c-FLIP/c-FLIPL Lentiviral expression plasmid for CFLAR lentivirus packaging, CFLAR lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP000484
Gene Name CFLAR
Accession Number NM_001127183
Gene ID 8837
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 1443 bp
Gene Alias c-FLIP,c-FLIPL,c-FLIPR,c-FLIPS,CASH,CASP8AP1,Casper,CLARP,FLAME,FLAME-1,FLAME1,FLIP,I-FLICE,MRIT
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGTCTGCTGAAGTCATCCATCAGGTTGAAGAAGCACTTGATACAGATGAGAAGGAGATGCTGCTCTTTTTGTGCCGGGATGTTGCTATAGATGTGGTTCCACCTAATGTCAGGGACCTTCTGGATATTTTACGGGAAAGAGGTAAGCTGTCTGTCGGGGACTTGGCTGAACTGCTCTACAGAGTGAGGCGATTTGACCTGCTCAAACGTATCTTGAAGATGGACAGAAAAGCTGTGGAGACCCACCTGCTCAGGAACCCTCACCTTGTTTCGGACTATAGAGTGCTGATGGCAGAGATTGGTGAGGATTTGGATAAATCTGATGTGTCCTCATTAATTTTCCTCATGAAGGATTACATGGGCCGAGGCAAGATAAGCAAGGAGAAGAGTTTCTTGGACCTTGTGGTTGAGTTGGAGAAACTAAATCTGGTTGCCCCAGATCAACTGGATTTATTAGAAAAATGCCTAAAGAACATCCACAGAATAGACCTGAAGACAAAAATCCAGAAGTACAAGCAGTCTGTTCAAGGAGCAGGGACAAGTTACAGGAATGTTCTCCAAGCAGCAATCCAAAAGAGTCTCAAGGATCCTTCAAATAACTTCAGGCTCCATAATGGGAGAAGTAAAGAACAAAGACTTAAGGAACAGCTTGGCGCTCAACAAGAACCAGTGAAGAAATCCATTCAGGAATCAGAAGCTTTTTTGCCTCAGAGCATACCTGAAGAGAGATACAAGATGAAGAGCAAGCCCCTAGGAATCTGCCTGATAATCGATTGCATTGGCAATGAGACAGAGCTTCTTCGAGACACCTTCACTTCCCTGGGCTATGAAGTCCAGAAATTCTTGCATCTCAGTATGCATGGTATATCCCAGATTCTTGGCCAATTTGCCTGTATGCCCGAGCACCGAGACTACGACAGCTTTGTGTGTGTCCTGGTGAGCCGAGGAGGCTCCCAGAGTGTGTATGGTGTGGATCAGACTCACTCAGGGCTCCCCCTGCATCACATCAGGAGGATGTTCATGGGAGATTCATGCCCTTATCTAGCAGGGAAGCCAAAGATGTTTTTTATTCAGAACTATGTGGTGTCAGAGGGCCAGCTGGAGGACAGCAGCCTCTTGGAGGTGGATGGGCCAGCGATGAAGAATGTGGAATTCAAGGCTCAGAAGCGAGGGCTGTGCACAGTTCACCGAGAAGCTGACTTCTTCTGGAGCCTGTGTACTGCGGACATGTCCCTGCTGGAGCAGTCTCACAGCTCACCATCCCTGTACCTGCAGTGCCTCTCCCAGAAACTGAGACAAGAAAGAAAACGCCCACTCCTGGATCTTCACATTGAACTCAATGGCTACATGTATGATTGGAACAGCAGAGTTTCTGCCAAGGAGAAATATTATGTCTGGCTGCAGCACACTCTGAGAAAGAAACTTATCCTCTCCTACACATAA
ORF Protein Sequence MSAEVIHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDILRERGKLSVGDLAELLYRVRRFDLLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYMGRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGTSYRNVLQAAIQKSLKDPSNNFRLHNGRSKEQRLKEQLGAQQEPVKKSIQESEAFLPQSIPEERYKMKSKPLGICLIIDCIGNETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYDSFVCVLVSRGGSQSVYGVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQNYVVSEGQLEDSSLLEVDGPAMKNVEFKAQKRGLCTVHREADFFWSLCTADMSLLEQSHSSPSLYLQCLSQKLRQERKRPLLDLHIELNGYMYDWNSRVSAKEKYYVWLQHTLRKKLILSYT

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-IP0138-Ab Anti-CFLAR monoclonal antibody
    Target Antigen GM-Tg-g-IP0138-Ag CFLAR protein
    ORF Viral Vector pGMLP000484 Human CFLAR Lentivirus plasmid
    ORF Viral Vector pGMAP000345 Human CFLAR Adenovirus plasmid
    ORF Viral Vector vGMLP000484 Human CFLAR Lentivirus particle
    ORF Viral Vector vGMAP000345 Human CFLAR Adenovirus particle


    Target information

    Target ID GM-IP0138
    Target Name CFLAR/FLIP
    Gene Group Identifier
    （Target Gene ID in Homo species)         		8837
    Gene ID 100068181 (Equus caballus), 100142680 (Felis catus), 117279 (Rattus norvegicus), 12633 (Mus musculus)
    488471 (Canis lupus familiaris), 497199 (Bos taurus), 574234 (Macaca mulatta), 8837 (Homo sapiens)
    Gene Symbols & Synonyms CFLAR,Cflar,FLIP,Flip,Cash,MRIT,CLARP,FLAME,Casper,Gm9845,c-Flip,FLAME-1,I-FLICE,2310024N18Rik,A430105C05Rik,CASH,cFLIP,FLAME1,c-FLIP,c-FLIPL,c-FLIPR,c-FLIPS,CASP8AP1
    Target Alternative Names 2310024N18Rik,A430105C05Rik,CASH,CASP8 and FADD-like apoptosis regulator,CASP8AP1,CFLAR,CLARP,Cash,Caspase homolog (CASH),Caspase-eight-related protein (Casper),Caspase-like apoptosis regulatory protein (CLARP),Casper,Cellular FLICE-like inhibitory protein (c-FLIP),Cflar,FADD-like antiapoptotic molecule 1 (FLAME-1),FLAME,FLAME-1,FLAME1,FLIP,Flip,Gm9845,I-FLICE,Inhibitor of FLICE (I-FLICE),MACH-related inducer of toxicity (MRIT),MRIT,Usurpin,c-FLIP,c-FLIPL,c-FLIPR,c-FLIPS,c-Flip,cFLIP
    Uniprot Accession O15519,O35732
    Additional SwissProt Accessions: O35732,O15519
    Uniprot Entry Name
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease cancer
    Disease from KEGG NF-kappa B signaling pathway, Apoptosis, TNF signaling pathway, Chagas disease, Hepatitis C
    Gene Ensembl ENSECAG00000021300, ENSMUSG00000026031, ENSCAFG00845029893, ENSBTAG00000010998, ENSMMUG00000012310, ENSG00000003402
    Target Classification Tumor-associated antigen (TAA)


    About GMVC

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    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.