Human SERPINE1/PAI/PAI-1 ORF/cDNA clone-Lentivirus plasmid (NM_000602)

Cat. No.: pGMLP000493
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human SERPINE1/PAI/PAI-1 Lentiviral expression plasmid for SERPINE1 lentivirus packaging, SERPINE1 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP000493
Gene Name SERPINE1
Accession Number NM_000602
Gene ID 5054
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 1209 bp
Gene Alias PAI,PAI-1,PAI1,PLANH1
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGCAGATGTCTCCAGCCCTCACCTGCCTAGTCCTGGGCCTGGCCCTTGTCTTTGGTGAAGGGTCTGCTGTGCACCATCCCCCATCCTACGTGGCCCACCTGGCCTCAGACTTCGGGGTGAGGGTGTTTCAGCAGGTGGCGCAGGCCTCCAAGGACCGCAACGTGGTTTTCTCACCCTATGGGGTGGCCTCGGTGTTGGCCATGCTCCAGCTGACAACAGGAGGAGAAACCCAGCAGCAGATTCAAGCAGCTATGGGATTCAAGATTGATGACAAGGGCATGGCCCCCGCCCTCCGGCATCTGTACAAGGAGCTCATGGGGCCATGGAACAAGGATGAGATCAGCACCACAGACGCGATCTTCGTCCAGCGGGATCTGAAGCTGGTCCAGGGCTTCATGCCCCACTTCTTCAGGCTGTTCCGGAGCACGGTCAAGCAAGTGGACTTTTCAGAGGTGGAGAGAGCCAGATTCATCATCAATGACTGGGTGAAGACACACACAAAAGGTATGATCAGCAACTTGCTTGGGAAAGGAGCCGTGGACCAGCTGACACGGCTGGTGCTGGTGAATGCCCTCTACTTCAACGGCCAGTGGAAGACTCCCTTCCCCGACTCCAGCACCCACCGCCGCCTCTTCCACAAATCAGACGGCAGCACTGTCTCTGTGCCCATGATGGCTCAGACCAACAAGTTCAACTATACTGAGTTCACCACGCCCGATGGCCATTACTACGACATCCTGGAACTGCCCTACCACGGGGACACCCTCAGCATGTTCATTGCTGCCCCTTATGAAAAAGAGGTGCCTCTCTCTGCCCTCACCAACATTCTGAGTGCCCAGCTCATCAGCCACTGGAAAGGCAACATGACCAGGCTGCCCCGCCTCCTGGTTCTGCCCAAGTTCTCCCTGGAGACTGAAGTCGACCTCAGGAAGCCCCTAGAGAACCTGGGAATGACCGACATGTTCAGACAGTTTCAGGCTGACTTCACGAGTCTTTCAGACCAAGAGCCTCTCCACGTCGCGCAGGCGCTGCAGAAAGTGAAGATCGAGGTGAACGAGAGTGGCACGGTGGCCTCCTCATCCACAGCTGTCATAGTCTCAGCCCGCATGGCCCCCGAGGAGATCATCATGGACAGACCCTTCCTCTTTGTGGTCCGGCACAACCCCACAGGAACAGTCCTTTTCATGGGCCAAGTGATGGAACCCTGA
ORF Protein Sequence MQMSPALTCLVLGLALVFGEGSAVHHPPSYVAHLASDFGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGFKIDDKGMAPALRHLYKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEVERARFIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNALYFNGQWKTPFPDSSTHRRLFHKSDGSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYHGDTLSMFIAAPYEKEVPLSALTNILSAQLISHWKGNMTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFRQFQADFTSLSDQEPLHVAQALQKVKIEVNESGTVASSSTAVIVSARMAPEEIIMDRPFLFVVRHNPTGTVLFMGQVMEP

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T15556-Ab Anti-PAI1/ SERPINE1/ PAI monoclonal antibody
    Target Antigen GM-Tg-g-T15556-Ag SERPINE1 VLP (virus-like particle)
    Cytokine cks-Tg-g-GM-T15556 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 (SERPINE1) protein & antibody
    ORF Viral Vector pGMLP000493 Human SERPINE1 Lentivirus plasmid
    ORF Viral Vector pGMLV002209 Human SERPINE1 Lentivirus plasmid
    ORF Viral Vector pGMAP000049 Human SERPINE1 Adenovirus plasmid
    ORF Viral Vector vGMLP000493 Human SERPINE1 Lentivirus particle
    ORF Viral Vector vGMLV002209 Human SERPINE1 Lentivirus particle
    ORF Viral Vector vGMAP000049 Human SERPINE1 Adenovirus particle


    Target information

    Target ID GM-T15556
    Target Name PAI-1/Serpin E1/SERPINE1
    Gene Group Identifier
    （Target Gene ID in Homo species)         		5054
    Gene ID 100033931 (Equus caballus), 100127105 (Felis catus), 18787 (Mus musculus), 24617 (Rattus norvegicus)
    281375 (Bos taurus), 403476 (Canis lupus familiaris), 5054 (Homo sapiens), 713883 (Macaca mulatta)
    Gene Symbols & Synonyms SERPINE1,Serpine1,PAI-1,PAI1,Planh1,Pai1,PAI1A,Planh,Pai1aa,RATPAI1A,PAI,PLANH1
    Target Alternative Names Endothelial plasminogen activator inhibitor,PAI,PAI-1,PAI1,PAI1A,PLANH1,Pai1,Pai1aa,Planh,Planh1,Plasminogen activator inhibitor 1,RATPAI1A,SERPINE1,Serpin E1,Serpine1
    Uniprot Accession P05121,P13909,P20961,P22777
    Additional SwissProt Accessions: P22777,P20961,P13909,P05121
    Uniprot Entry Name
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target, Cytokine Target
    Disease cancer, Ovary Cancer, Malignant neoplasm of bladder
    Disease from KEGG HIF-1 signaling pathway, p53 signaling pathway, Cellular senescence, Hippo signaling pathway, Complement and coagulation cascades, AGE-RAGE signaling pathway in diabetic complications, Chagas disease
    Gene Ensembl ENSECAG00000019781, ENSMUSG00000037411, ENSCAFG00845000607, ENSG00000106366, ENSMMUG00000009926
    Target Classification


    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.