Human DHFR/DHFRP1/DYR ORF/cDNA clone-Lentivirus plasmid (NM_000791)

Cat. No.: pGMLP000510
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human DHFR/DHFRP1/DYR Lentiviral expression plasmid for DHFR lentivirus packaging, DHFR lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP000510
Gene Name DHFR
Accession Number NM_000791
Gene ID 1719
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 564 bp
Gene Alias DHFRP1,DYR
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGGTTGGTTCGCTAAACTGCATCGTCGCTGTGTCCCAGAACATGGGCATCGGCAAGAACGGGGACCTGCCCTGGCCACCGCTCAGGAATGAATTCAGATATTTCCAGAGAATGACCACAACCTCTTCAGTAGAAGGTAAACAGAATCTGGTGATTATGGGTAAGAAGACCTGGTTCTCCATTCCTGAGAAGAATCGACCTTTAAAGGGTAGAATTAATTTAGTTCTCAGCAGAGAACTCAAGGAACCTCCACAAGGAGCTCATTTTCTTTCCAGAAGTCTAGATGATGCCTTAAAACTTACTGAACAACCAGAATTAGCAAATAAAGTAGACATGGTCTGGATAGTTGGTGGCAGTTCTGTTTATAAGGAAGCCATGAATCACCCAGGCCATCTTAAACTATTTGTGACAAGGATCATGCAAGACTTTGAAAGTGACACGTTTTTTCCAGAAATTGATTTGGAGAAATATAAACTTCTGCCAGAATACCCAGGTGTTCTCTCTGATGTCCAGGAGGAGAAAGGCATTAAGTACAAATTTGAAGTATATGAGAAGAATGATTAA
ORF Protein Sequence MVGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFSIPEKNRPLKGRINLVLSRELKEPPQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGGSSVYKEAMNHPGHLKLFVTRIMQDFESDTFFPEIDLEKYKLLPEYPGVLSDVQEEKGIKYKFEVYEKND

Reference




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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T17345-Ab Anti-DHFR monoclonal antibody
    Target Antigen GM-Tg-g-T17345-Ag DHFR protein
    ORF Viral Vector pGMLP000510 Human DHFR Lentivirus plasmid
    ORF Viral Vector pGMAP000102 Human DHFR Adenovirus plasmid
    ORF Viral Vector vGMLP000510 Human DHFR Lentivirus particle
    ORF Viral Vector vGMAP000102 Human DHFR Adenovirus particle


    Target information

    Target ID GM-T17345
    Target Name DHFR
    Gene Group Identifier
    （Target Gene ID in Homo species)         		1719
    Gene ID 100073256 (Equus caballus), 101087964 (Felis catus), 13361 (Mus musculus), 1719 (Homo sapiens)
    24312 (Rattus norvegicus), 479165 (Canis lupus familiaris), 508809 (Bos taurus), 711268 (Macaca mulatta)
    Gene Symbols & Synonyms DHFR,Dhfr,8430436I03Rik,DYR,DHFR1,DHFRP1,Dhfr1
    Target Alternative Names 8430436I03Rik,DHFR,DHFR1,DHFRP1,DYR,Dhfr,Dhfr1,Dihydrofolate reductase
    Uniprot Accession P00374,P00375,P00376,Q920D2
    Additional SwissProt Accessions: P00375,P00374,Q920D2,P00376
    Uniprot Entry Name
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease cancer
    Disease from KEGG Metabolic pathways, Antifolate resistance
    Gene Ensembl ENSECAG00000026827, ENSMUSG00000021707, ENSG00000228716, ENSCAFG00845005830, ENSBTAG00000007681, ENSMMUG00000018283
    Target Classification Tumor-associated antigen (TAA)


    About GMVC

    GDU

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