Human GSK3B ORF/cDNA clone-Mammalian (Non-Viral Vector) plasmid (NM_001146156.2)

Cat. No.: pGMPC000726
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human GSK3B/ Non-Viral expression plasmid (overexpression vector) for mouse GSK3B overexpression in unique cell transient transfection and stable cell line development.

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Product Description

Catalog ID pGMPC000726
Gene Name GSK3B
Accession Number NM_001146156.2
Gene ID 2932
Species Human
Product Type Mammalian (Non-Viral Vector) plasmid (overexpression)
Insert Length 1263 bp
Gene Alias
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag Null
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGTCAGGGCGGCCCAGAACCACCTCCTTTGCGGAGAGCTGCAAGCCGGTGCAGCAGCCTTCAGCTTTTGGCAGCATGAAAGTTAGCAGAGACAAGGACGGCAGCAAGGTGACAACAGTGGTGGCAACTCCTGGGCAGGGTCCAGACAGGCCACAAGAAGTCAGCTATACAGACACTAAAGTGATTGGAAATGGATCATTTGGTGTGGTATATCAAGCCAAACTTTGTGATTCAGGAGAACTGGTCGCCATCAAGAAAGTATTGCAGGACAAGAGATTTAAGAATCGAGAGCTCCAGATCATGAGAAAGCTAGATCACTGTAACATAGTCCGATTGCGTTATTTCTTCTACTCCAGTGGTGAGAAGAAAGATGAGGTCTATCTTAATCTGGTGCTGGACTATGTTCCGGAAACAGTATACAGAGTTGCCAGACACTATAGTCGAGCCAAACAGACGCTCCCTGTGATTTATGTCAAGTTGTATATGTATCAGCTGTTCCGAAGTTTAGCCTATATCCATTCCTTTGGAATCTGCCATCGGGATATTAAACCGCAGAACCTCTTGTTGGATCCTGATACTGCTGTATTAAAACTCTGTGACTTTGGAAGTGCAAAGCAGCTGGTCCGAGGAGAACCCAATGTTTCGTATATCTGTTCTCGGTACTATAGGGCACCAGAGTTGATCTTTGGAGCCACTGATTATACCTCTAGTATAGATGTATGGTCTGCTGGCTGTGTGTTGGCTGAGCTGTTACTAGGACAACCAATATTTCCAGGGGATAGTGGTGTGGATCAGTTGGTAGAAATAATCAAGGTCCTGGGAACTCCAACAAGGGAGCAAATCAGAGAAATGAACCCAAACTACACAGAATTTAAATTCCCTCAAATTAAGGCACATCCTTGGACTAAGGTCTTCCGACCCCGAACTCCACCGGAGGCAATTGCACTGTGTAGCCGTCTGCTGGAGTATACACCAACTGCCCGACTAACACCACTGGAAGCTTGTGCACATTCATTTTTTGATGAATTACGGGACCCAAATGTCAAACTACCAAATGGGCGAGACACACCTGCACTCTTCAACTTCACCACTCAAGAACTGTCAAGTAATCCACCTCTGGCTACCATCCTTATTCCTCCTCATGCTCGGATTCAAGCAGCTGCTTCAACCCCCACAAATGCCACAGCAGCGTCAGATGCTAATACTGGAGACCGTGGACAGACCAATAATGCTGCTTCTGCATCAGCTTCCAACTCCACCTGA
ORF Protein Sequence MSGRPRTTSFAESCKPVQQPSAFGSMKVSRDKDGSKVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPNVKLPNGRDTPALFNFTTQELSSNPPLATILIPPHARIQAAASTPTNATAASDANTGDRGQTNNAASASASNST

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T70977-Ab Anti-GSK-3B monoclonal antibody
    Target Antigen GM-Tg-g-T70977-Ag GSK-3B/GSK3B protein
    ORF Viral Vector pGMLP005802 Human GSK3B Lentivirus plasmid
    ORF Viral Vector pGMAD001170 Human GSK3B Adenovirus plasmid
    ORF Viral Vector pGMAAV000150 Human GSK3B Adeno-associate virus(AAV) plasmid
    ORF Viral Vector pGMAAV001480 Human GSK3B Adeno-associate virus(AAV) plasmid
    ORF Viral Vector pGMLP-SPh-089 Human GSK3B Lentivirus plasmid
    ORF Viral Vector pGMLP-SPh-134 Human GSK3B Lentivirus plasmid
    ORF Viral Vector pGMAP-SPh-229 Human GSK3B Adenovirus plasmid
    ORF Viral Vector pGMAP-SPh-274 Human GSK3B Adenovirus plasmid
    ORF Viral Vector pGMPC000126 Human GSK3B Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC000726 Human GSK3B Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP005802 Human GSK3B Lentivirus particle
    ORF Viral Vector vGMAD001170 Human GSK3B Adenovirus particle
    ORF Viral Vector vGMAAV000150 Human GSK3B Adeno-associate virus(AAV) particle
    ORF Viral Vector vGMAAV001480 Human GSK3B Adeno-associate virus(AAV) particle
    ORF Viral Vector vGMLP-SPh-089 Human GSK3B Lentivirus particle
    ORF Viral Vector vGMLP-SPh-134 Human GSK3B Lentivirus particle
    ORF Viral Vector vGMAP-SPh-229 Human GSK3B Adenovirus particle
    ORF Viral Vector vGMAP-SPh-274 Human GSK3B Adenovirus particle


    Target information

    Target ID GM-T70977
    Target Name GSK3B/GSK-3B
    Gene Group Identifier
    （Target Gene ID in Homo species)         		2932
    Gene ID 100061033 (Equus caballus), 101081660 (Felis catus), 2932 (Homo sapiens), 478575 (Canis lupus familiaris)
    56637 (Mus musculus), 713114 (Macaca mulatta), 790875 (Bos taurus), 84027 (Rattus norvegicus)
    Gene Symbols & Synonyms GSK3B,Gsk3b,GSK3,GSK-3,GSK-3beta,7330414F15Rik,8430431H08Rik,GSK3beta
    Target Alternative Names 7330414F15Rik,8430431H08Rik,GSK-3,GSK-3 beta,GSK-3B,GSK-3beta,GSK3,GSK3B,GSK3beta,Glycogen synthase kinase-3 beta,Gsk3b,Serine/threonine-protein kinase GSK3B
    Uniprot Accession P18266,P49841,Q9WV60
    Additional SwissProt Accessions: P49841,Q9WV60,P18266
    Uniprot Entry Name
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease
    Disease from KEGG EGFR tyrosine kinase inhibitor resistance, ErbB signaling pathway, Chemokine signaling pathway, PI3K-Akt signaling pathway, Wnt signaling pathway, Axon guidance, Hippo signaling pathway, Focal adhesion, Signaling pathways regulating pluripotency of stem cells, IL-17 signaling pathway, T cell receptor signaling pathway, B cell receptor signaling pathway, Neurotrophin signaling pathway, Melanogenesis, Prolactin signaling pathway, Thyroid hormone signaling pathway, Insulin resistance, Cushing syndrome, Growth hormone synthesis, secretion and action, Alcoholic liver disease, Alzheimer disease, Yersinia infection, Hepatitis C, Measles, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Colorectal cancer, Endometrial cancer, Prostate cancer, Basal cell carcinoma, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Lipid and atherosclerosis
    Gene Ensembl ENSECAG00000024935, ENSG00000082701, ENSCAFG00845017754, ENSMUSG00000022812, ENSMMUG00000001980, ENSBTAG00000048057
    Target Classification Kinase, Pathway


    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.