YWHAQ: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of YWHAQ. The page also collects GeneMedi's different modalities and formats products for YWHAQ in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the YWHAQ target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Introcelluar Protein.
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. [provided by RefSeq, Jul 2008]
| Target ID | GM-IP2293 |
| Target Name | YWHAQ |
| Gene ID | 10971,22630,25577,694702,607060,101088481,768311,100057123 |
| Gene Symbol and Synonyms | 14-3-3,14-3-3t,1C5,2700028P07Rik,HS1,YWHAQ |
| Uniprot Accession | P27348,P68255,Q3SZI4 |
| Uniprot Entry Name | 1433T_HUMAN,1433T_RAT,1433T_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | Lung Cancer |
| Gene Ensembl | ENSG00000134308 |
| Target Classification | N/A |
Pre-made anti-YWHAQ inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-YWHAQ monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-YWHAQ mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
| Antibody Name | Species | Format | Classified by tag | Detail |
| Anti-YWHAQ monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | Detail |
Recombinant multi-species 1433T/ YWHAQ/ 2014-3-3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine YWHAQ protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
| Products Name | Species | Expression Platform | Detail |
| YWHAQ protein | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Detail |
Pre-made YWHAQ viral vector in GM Promise-ORFTM
| Cat No. | Products name | NM ID | Species | Type | Detail |
| vGMAP000259 | Human YWHAQ Adenovirus particle | BC056867 | Human | Adenovirus particle | Detail |
| vGMLP000536 | human YWHAQ Lentivirus particle | NM_006826 | Human | Lentivirus particle | Detail |
| pGMLP000536 | human YWHAQ Lentivirus plasmid | NM_006826 | Human | Lentivirus plasmid | Detail |
| pGMAP000259 | Human YWHAQ Adenovirus plasmid | BC056867 | Human | Adenovirus plasmid | Detail |
| pGMLPm000471 | mouse Ywhaq Lentivirus plasmid | NM_011739 | Mouse | Lentivirus plasmid | Detail |
| vGMLPm000471 | mouse Ywhaq Lentivirus particle | NM_011739 | Mouse | Lentivirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.