FCER1A: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of FCER1A. The page also collects GeneMedi's different modalities and formats products for FCER1A in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the FCER1A target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Transmembrane Protein.
The immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response. When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine that are responsible for allergy symptoms are released. This receptor is comprised of an alpha subunit, a beta subunit, and two gamma subunits. The protein encoded by this gene represents the alpha subunit. [provided by RefSeq, Aug 2011]
| Target ID | GM-MP0438 |
| Target Name | FCER1A |
| Gene ID | 2205,14125,25047,719324,478970,101094323,506783,100057308 |
| Gene Symbol and Synonyms | FCE1A,fcepsilonri,FCER1A,FcERI,FCERIA,Fcr-5,Iger01,RATIGER01 |
| Uniprot Accession | P12319,P12371 |
| Uniprot Entry Name | FCERA_HUMAN,FCERA_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | Prostate Cancer |
| Gene Ensembl | ENSG00000179639 |
| Target Classification | N/A |
Pre-made anti-FCER1A inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-FCER1A benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-FCER1A mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
| Antibody Name | Species | Format | Classified by tag | Detail |
| Anti-FCER1A monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | FACS/Biofunctional Antibody | Detail |
Multi-species FCERA/ FCER1A/ FCE1A VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FCER1A VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
| Products Name | Species | Expression Platform | Detail |
| FCER1A VLP (virus-like particle) | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Products Developing |
Pre-made FCER1A viral vector in GM Promise-ORFTM
| Cat No. | Products name | NM ID | Species | Type | Detail |
| pGMLP000440 | human FCER1A Lentivirus plasmid | NM_002001 | Human | Lentivirus plasmid | Detail |
| vGMLP000440 | human FCER1A Lentivirus particle | NM_002001 | Human | Lentivirus particle | Detail |
| pGMLPm000811 | mouse Fcer1a Lentivirus plasmid | NM_010184 | Mouse | Lentivirus plasmid | Detail |
| vGMLPm000811 | mouse Fcer1a Lentivirus particle | NM_010184 | Mouse | Lentivirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.