PDPK1: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of PDPK1. The page also collects GeneMedi's different modalities and formats products for PDPK1 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the PDPK1 target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Introcelluar Protein.
Enables 3-phosphoinositide-dependent protein kinase activity; phospholipase activator activity; and phospholipase binding activity. Involved in several processes, including cell surface receptor signaling pathway; regulation of protein kinase activity; and regulation of signal transduction. Acts upstream of or within intracellular signal transduction. Located in cell projection; cytosol; and plasma membrane. Implicated in prostate cancer. Biomarker of lung non-small cell carcinoma. [provided by Alliance of Genome Resources, Apr 2022]
| Target ID | GM-T20891 |
| Target Name | PDPK1 |
| Gene ID | 5170,18607,81745,697523,479875,101101686,100138102,100630736 |
| Gene Symbol and Synonyms | PDK1,PDPK1,PDPK2,PDPK2P,PRO0461 |
| Uniprot Accession | O15530,O55173 |
| Uniprot Entry Name | PDPK1_HUMAN,PDPK1_RAT |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | Cancer |
| Gene Ensembl | ENSG00000140992 |
| Target Classification | Kinase, Tumor-associated antigen (TAA) |
Pre-made anti-PDPK1 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-PDPK1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-PDPK1 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
| Antibody Name | Species | Format | Classified by tag | Detail |
| Anti-PDPK1 monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | Therapeutics Target antibody | Detail |
Recombinant multi-species PDPK1/ PDK1/ PDPK2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PDPK1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
| Products Name | Species | Expression Platform | Detail |
| PDPK1 protein | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Detail |
Pre-made PDPK1 viral vector in GM Promise-ORFTM
| Cat No. | Products name | NM ID | Species | Type | Detail |
| vGMAP000177 | Human PDPK1 Adenovirus particle | BC006339 | Human | Adenovirus particle | Detail |
| pGMAP000177 | Human PDPK1 Adenovirus plasmid | BC006339 | Human | Adenovirus plasmid | Detail |
| vGMLP000515 | human PDPK1 Lentivirus particle | NM_031268 | Human | Lentivirus particle | Detail |
| pGMLP000515 | human PDPK1 Lentivirus plasmid | NM_031268 | Human | Lentivirus plasmid | Detail |
| pGMAD000244 | mouse Pdpk1 Adenovirus plasmid | NM_011062.4 | Mouse | Adenovirus plasmid | Detail |
| vGMAD000244 | mouse Pdpk1 Adenovirus particle | NM_011062.4 | Mouse | Adenovirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.