INHBA: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of INHBA. The page also collects GeneMedi's different modalities and formats products for INHBA in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the INHBA target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate a subunit of the dimeric activin and inhibin protein complexes. These complexes activate and inhibit, respectively, follicle stimulating hormone secretion from the pituitary gland. The encoded protein also plays a role in eye, tooth and testis development. Elevated expression of this gene may be associated with cancer cachexia in human patients. [provided by RefSeq, Aug 2016]
| Target ID | GM-TA010 |
| Target Name | INHBA |
| Gene ID | 3624,16323,29200,702734,483245,493853,281867,100034076 |
| Gene Symbol and Synonyms | EDF,FRP,INHBA |
| Uniprot Accession | P08476,P18331,Q6X2S4,P07995,P55102 |
| Uniprot Entry Name | INHBA_HUMAN,INHBA_RAT,INHBA_FELCA,INHBA_BOVIN,INHBA_HORSE |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Therapeutics Target, INN Index |
| Disease | N/A |
| Gene Ensembl | ENSG00000122641 |
| Target Classification | N/A |
Pre-made INHBA-specific INN-index biosimilar (antibody&conjugates)
Anti-INHBA therapeutic INN-index antibodies and conjugates are biosimilars expressed by mammalian cell line as a benchmark reference therapeutic antibody for drug discovery, target MOA research, cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
| Cat No. | Products Name (INN Index) | INN Name | Previous Name | Target | Format | Detail |
| GMP-Bios-ab-234 | Pre-Made Garetosmab biosimilar, Whole mAb, Anti-INHBA/ACT Antibody: Anti-EDF/FRP therapeutic antibody | Garetosmab | INHBA/ACT | Whole mAb | Detail | |
| GMP-Bios-INN-998 | Pre-Made Sotatercept Biosimilar, Fusion Protein targeting INHBA/ACT fused with human IGHG1 Fc (Fragment constant): Recombinant therapeutic protein targeting EDF/FRP | sotatercept | INHBA/ACT | Fusion Protein | Detail |
Click to check more INN-indexed antibody & protein biosimilar
Pre-made anti-INHBA inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-INHBA benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-INHBA mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
| Antibody Name | Species | Format | Classified by tag | Detail |
| Anti-INHBA monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Recombinant multi-species INHBA/ EDF/ FRP protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine INHBA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
| Products Name | Species | Expression Platform | Detail |
| INHBA protein | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Detail |
Pre-made INHBA viral vector in GM Promise-ORFTM
| Cat No. | Products name | NM ID | Species | Type | Detail |
| pGMLP000143 | human INHBA Lentivirus plasmid | NM_002192 | Human | Lentivirus plasmid | Detail |
| vGMLP000143 | human INHBA Lentivirus particle | NM_002192 | Human | Lentivirus particle | Detail |
| pGMLPm001518 | mouse Inhba Lentivirus plasmid | NM_008380 | Mouse | Lentivirus plasmid | Detail |
| vGMLPm001518 | mouse Inhba Lentivirus particle | NM_008380 | Mouse | Lentivirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.