SUMO1: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of SUMO1. The page also collects GeneMedi's different modalities and formats products for SUMO1 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the SUMO1 target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Introcelluar Protein.
This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last four amino acids of the carboxy-terminus have been cleaved off. Several pseudogenes have been reported for this gene. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008]
| Target ID | GM-TA023 |
| Target Name | SUMO1 |
| Gene ID | 7341,22218,301442,703644,478874,101095673,614967,100067107 |
| Gene Symbol and Synonyms | DAP1,GMP1,OFC10,PIC1,SENP2,SENTRIN,SMT3,SMT3C,SMT3H3,SMTP3,SUMO-1,SUMO1,UBL1 |
| Uniprot Accession | P63165,Q5I0H3,Q5E9D1 |
| Uniprot Entry Name | SUMO1_HUMAN,SUMO1_RAT,SUMO1_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | Cancer |
| Gene Ensembl | ENSG00000116030 |
| Target Classification | Tumor-associated antigen (TAA) |
Pre-made anti-SUMO1 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-SUMO1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-SUMO1 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
| Antibody Name | Species | Format | Classified by tag | Detail |
| Anti-SUMO1 monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | Therapeutics Target antibody | Detail |
Recombinant multi-species SUMO1/ DAP1/ GMP1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SUMO1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
| Products Name | Species | Expression Platform | Detail |
| SUMO1 protein | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Detail |
Pre-made SUMO1 viral vector in GM Promise-ORFTM
| Cat No. | Products name | NM ID | Species | Type | Detail |
| vGMAP000313 | Human SUMO1 Adenovirus particle | BC006462 | Human | Adenovirus particle | Detail |
| pGMLP000463 | human SUMO1 Lentivirus plasmid | NM_003352 | Human | Lentivirus plasmid | Detail |
| pGMAP000313 | Human SUMO1 Adenovirus plasmid | BC006462 | Human | Adenovirus plasmid | Detail |
| vGMLP000463 | human SUMO1 Lentivirus particle | NM_003352 | Human | Lentivirus particle | Detail |
| pGMLPm003735 | mouse Sumo1 Lentivirus plasmid | NM_009460.2 | Mouse | Lentivirus plasmid | Detail |
| vGMLPm003735 | mouse Sumo1 Lentivirus particle | NM_009460.2 | Mouse | Lentivirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.